Facilities
IVC (Individually Ventilated Cages) Housing System
The cages are equipped with a HEPA filter that allows air to enter at the same pressure, speed, and temperature into each single cage.
Automatic Hematology Analyzer (Hemavet 950 FS, Drew Scientific Group)
Fully automated system used to assess haematological parameters for laboratory animals (mice, rats, guinea pigs, rabbits).
The hematology system determines 20 parameters: WBC, NE#, NE%, LY#, LY%, MO#, MO%, EO#, EO%, BA#, BA%, RBC, Hb, HCT, MCV, MCH, MCHC, RDW, MPV, PLT.
Metabolic cages for mice and rats
The metabolic cages allow measurement of food and water intake, as well as the separation and collection of urine and feces used for numerous qualitative and quantitative determinations.
VEVO 2100 Ultrasound System for laboratory animals (rodents)
Ultrasound imaging is an imaging technique providing real-time anatomical and physiological information. The VEVO 2100 Ultrasound System is easy to use, non-invasive and fast. The system is used for cardiac and general ultrasound in mice and rats.
Tail-Flick
The tail-flick test is a test of nociception used in rodents. The tail flick test involves application of a heat stimulus to the tail of animal (mouse or rat), and the time taken for the tail to “flick” or twitch is recorded.
Plethysmometer
Device to measure paw volume and its changes (swelling) in rodents. Is a useful tool to evaluate the inflammatory response in experimental models and to screen potential anti-inflammatory or anti-oedema properties of tested compounds.
Hot/Cold Plate
The Hot/Cold plate is used for testing animal's thermal sensitivity to pain resulting from exposure to heat or cold, being a useful tool for analgesic drug screening using expermental models (rodents).
ROTAROD APPARATUS
The device is used to assess the effect of drugs on the motor coordination or fatigue resistance on rodents. The “Rota-Rod” technique is essential in screening drugs potentially active, or having side effects, on motor coordination.
Passive avoidance apparatus
The device is used to evaluate learning and memory in animal models of central nervous system disorders. Passive Avoidance Test is used to assess memory function based on the association formed between a specific environmental context, which the animal learns to avoid, and an aversive stimulus, represented by a mild foot shock. The device is divided into two compartments, one is dimly lit and preferable to animals, and the other is brightly lit.
CatWalk™XT System
CatWalk™XT System is a highly sensitive tool for assesing gait and locomotion in laboratory animals, mainly rodents. Basically, the laboratory animal traverses a glass plate, illuminated Footprints Technology captures the actual footprint with a high-speed video camera for maximum spatial and temporal resolution. The animals are moving freely giving the perfect physiological gait registration. The System has a software that visualizes foot prints and calculates the statistics related to the foot-print dimensions, time and distance relationship between footfalls. The method is validated in various disease models such as Parkinson’s disease, spinal cord injury, neuropathic pain, cerebellar ataxia, neuroageing and many more neurological altered diseases.
COMPACT RADIAL MAZE
The radial maze is a common test of spatial memory in rodents. Both spatial memory (place learning) and non-spatial memory (associative learning) can be evaluated in the radial maze. This system relies on the natural tendency of rodents to explore, learn, and remember different spatial locations.
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